MAPPFinder 2.0 Results for the Gene Ontology File: C:\Documents and Settings\icastane\Desktop\H_pylori_Master_20111130_KD.gex Table: HP0906 Results-Criterion1-GO Database: C:\Documents and Settings\icastane\Desktop\Hp-Std_External_20101130.gdb colors:|HP0906 KO| 11/19/2010 Helicobacter pylori Pvalues = true Calculation Summary: 114 probes met the [Average LogFC hp0906KO] < -0.25 AND [hp0906KO Tdist] < 0.05 criteria. 111 probes meeting the filter linked to a UniProt ID. 58 genes meeting the criterion linked to a GO term. 3429 Probes in this dataset 3379 Probes linked to a UniProt ID. 1021 Genes linked to a GO term. The z score is based on an N of 1021 and a R of 58 distinct genes in the GO. GOID GO Name GO Type Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 40029 "regulation of gene expression, epigenetic" P 6 21 22 28.57143 95.45454 4.577 0.002 0.478 5622 intracellular C 8 324 324 2.469136 100 -3.021 0.004 1 44425 membrane part C 15 141 141 10.6383 100 2.738 0.008 1 43412 macromolecule modification P 8 69 70 11.5942 98.57143 2.197 0.038 1 34641 cellular nitrogen compound metabolic process P 24 321 322 7.476635 99.68944 1.678 0.106 1 51536 iron-sulfur cluster binding F 4 34 34 11.76471 100 1.558 0.114 1 6950 response to stress P 5 47 47 10.6383 100 1.503 0.205 1 6810 transport P 12 151 151 7.94702 100 1.303 0.247 1 16051 carbohydrate biosynthetic process P 4 40 40 10 100 1.203 0.272 1 17111 nucleoside-triphosphatase activity F 7 86 86 8.139535 100 1.029 0.326 1 16818 "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides" F 7 90 90 7.777778 100 0.9 0.466 1 16817 "hydrolase activity, acting on acid anhydrides" F 7 90 90 7.777778 100 0.9 0.466 1 6139 "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" P 16 239 240 6.694561 99.58334 0.773 0.482 1 51179 localization P 12 172 172 6.976744 100 0.805 0.485 1 8152 metabolic process P 35 665 666 5.263158 99.84985 -0.787 0.485 1 44237 cellular metabolic process P 28 543 544 5.156538 99.81618 -0.771 0.489 1 3674 molecular_function F 50 914 916 5.470459 99.78166 -0.848 0.504 1 55085 transmembrane transport P 4 47 47 8.510638 100 0.858 0.507 1 32553 ribonucleotide binding F 9 199 199 4.522613 100 -0.786 0.51 1 32555 purine ribonucleotide binding F 9 199 199 4.522613 100 -0.786 0.51 1 16788 "hydrolase activity, acting on ester bonds" F 4 51 51 7.843137 100 0.684 0.523 1 9987 cellular process P 35 652 653 5.368098 99.84686 -0.573 0.54 1 3824 catalytic activity F 39 649 650 6.009245 99.84615 0.599 0.576 1 8150 biological_process P 50 851 852 5.875441 99.88263 0.601 0.602 1 16740 transferase activity F 13 199 200 6.532663 99.5 0.578 0.607 1 17076 purine nucleotide binding F 10 210 210 4.761905 100 -0.645 0.618 1 16070 RNA metabolic process P 4 95 95 4.210526 100 -0.65 0.64 1 44271 cellular nitrogen compound biosynthetic process P 8 121 121 6.61157 100 0.471 0.681 1 10467 gene expression P 9 180 181 5 99.44752 -0.435 0.74 1 166 nucleotide binding F 12 234 234 5.128205 100 -0.416 0.762 1 6519 cellular amino acid and derivative metabolic process P 4 81 81 4.938272 100 -0.301 0.792 1 16491 oxidoreductase activity F 6 94 94 6.382979 100 0.309 0.805 1 50896 response to stimulus P 5 71 71 7.042253 100 0.514 0.81 1 32559 adenyl ribonucleotide binding F 9 175 175 5.142857 100 -0.338 0.855 1 5524 ATP binding F 9 175 175 5.142857 100 -0.338 0.855 1 1882 nucleoside binding F 10 187 187 5.347594 100 -0.218 0.864 1 1883 purine nucleoside binding F 10 186 186 5.376344 100 -0.198 0.871 1 30554 adenyl nucleotide binding F 10 186 186 5.376344 100 -0.198 0.871 1 44281 small molecule metabolic process P 14 232 233 6.034483 99.57082 0.265 0.882 1 43170 macromolecule metabolic process P 19 352 353 5.397727 99.71671 -0.283 0.902 1 46394 carboxylic acid biosynthetic process P 4 62 62 6.451613 100 0.27 1 1 16053 organic acid biosynthetic process P 4 62 62 6.451613 100 0.27 1 1 GO Gene Ontology r 58 1021 1023 5.680705 99.8045 0 1 1 44260 cellular macromolecule metabolic process P 18 317 318 5.678234 99.68553 -0.002 1 1 46483 heterocycle metabolic process P 5 90 90 5.555555 100 -0.054 1 1 44283 small molecule biosynthetic process P 7 126 126 5.555555 100 -0.065 1 1 55114 oxidation reduction P 5 91 91 5.494505 100 -0.08 1 1 5975 carbohydrate metabolic process P 4 74 74 5.405406 100 -0.106 1 1 16787 hydrolase activity F 12 219 219 5.479452 100 -0.145 1 1 6082 organic acid metabolic process P 6 113 113 5.309734 100 -0.181 1 1 43436 oxoacid metabolic process P 6 113 113 5.309734 100 -0.181 1 1 19752 carboxylic acid metabolic process P 6 113 113 5.309734 100 -0.181 1 1 9308 amine metabolic process P 5 95 95 5.263158 100 -0.185 1 1 42180 cellular ketone metabolic process P 6 114 114 5.263158 100 -0.204 1 1 6520 cellular amino acid metabolic process P 4 78 78 5.128205 100 -0.219 1 1 44106 cellular amine metabolic process P 4 79 79 5.063291 100 -0.247 1 1